New Multi-Tumor Syndrome Identified

​ Researchers have now discovered that a set of mutations known to play a role in colorectal cancer predisposes individuals to a multi-tumor syndrome that increases risk for breast cancer and other cancers. "We presumed to know all multi-tumor syndromes, but we have taken yet another step in identifying cancer genes," stated Nicoline Hoogerbrugge, MD, PhD, Professor of Hereditary Cancer at Radboud University Medical Center and one of the authors of the study, which was published in Cancer Cell ....
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Fighting Breast Cancer: Around Half a Million Lives Saved

​ From 1975 to 1990, mortality rates for US women with breast cancer increased by 0.4% per year. Since then, breast cancer mortality rates have declined between 1.8% and 3.4% per year, resulting in between 384,000 and 614,500 saved lives, according to a new study published in the journal Cancer . "Recent reviews of mammography screening have focused media attention on some of the risks of mammography screening, such as callbacks for additional imaging and breast biopsies, downplaying the most im...
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Metastasis Risk in Postpartum Breast Cancer: An Interview With Virginia Borges, MD, MMSc

​In their previous research, Virginia F. Borges, MD, MMSc, and colleagues identified an increased risk of metastasis for women diagnosed with breast cancer within five years after giving birth. However, in their latest study, Dr. Borges and her fellow researchers from the University of Colorado Cancer Center and Oregon Health & Science University found that the increased risk of metastasis actually lasts for 10 years after the most recent childbirth. In this interview with i3 Health, Dr. Bor...
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Using a Diabetes Drug to Help Fight Breast Cancer

​ Researchers at the University of Helsinki, Finland, have found a new use for the diabetes drug metformin in a combination treatment that is effective against MYC-driven breast cancer. Around half of breast tumors have increased levels of the MYC protein, an oncogenic transcription factor that is often overexpressed in cancers. Overexpression and amplification of the MYC gene have been linked to breast tumor progression and increased risk of relapse and death. Even though MYC plays a role ...
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For Breast Cancer Survivors With Failed Implant-Based Reconstruction, Autologous Reconstruction Is Successful

After a mastectomy for breast cancer, patients have two options for breast reconstructive surgery: implant-based reconstruction or autologous reconstruction, which uses skin, fat, and sometimes muscle from another location in the body to form a breast shape. Although implant-based reconstruction, which is used in around 80% of patients, generally has high satisfaction rates, it sometimes leaves patients with physical pain, a feeling of tightness, or a poor aesthetic result. Other implant-based r...
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