Genetic Factor Found in Esophageal Cancer’s Racial Disparity

Why is esophageal adenocarcinoma (EAC) significantly more common among European Americans than among African Americans, even though both groups experience similar rates of gastroesophageal reflux disease (GERD), a relative risk factor for this condition? Researchers have found the reason, along with a potential means to end this disparity. "We've known for a long time that esophageal adenocarcinoma primarily affects Caucasians and very rarely affects African Americans," stated David G. Beer, PhD...
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Researchers Identify Genetic Mutations in Appendix Cancer

Because cancer of the appendix is rare and has not been adequately researched, patients with appendiceal neoplasms often receive chemotherapy treatments that are intended for colorectal cancer. However, in a study recently published in JCO Precision Oncology , researchers found that appendiceal tumors had clear molecular differences compared with colorectal cancers and other cancers. Senior author Olivier Harismendy, PhD, assistant professor of medicine at University of California San Diego Moor...
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