NSAIDs Increase Survival for PIK3CA-altered Head and Neck Cancer

According to a new study, over-the-counter non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin, have been found to significantly increase survival in patients with PIK3CA-altered head and neck squamous cell carcinoma (HNSCC).A mutation in PIK3CA, the gene encoding p110a and the catalytic subunit of phosphoinositide-(3)-kinase a, commonly occurs in HNSCC. In prior research, a sample of 504 patients with HNSCC tumors yielded 174 tumors containing a PIK3CA mutation. In patients with HNS...
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Throat, Not Cervix, Is Now Most Common HPV-Linked Cancer Site

According to a new report published by the Centers for Disease Control and Prevention (CDC), oropharyngeal squamous cell carcinoma (SCC), a cancer of the throat, has replaced cervical carcinoma as the cancer most commonly associated with human papillomavirus (HPV).Human papillomavirus, the most commonly sexually transmitted infection in the United States, is a known cause of cervical cancer and some types of oropharyngeal, vaginal, vulvar, penile, and anal cancers. According to the CDC report, r...
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Best Practices in Thyroid Cancer Management With Jochen H. Lorch, MD, MS

Thyroid cancer is one of the most prevalent cancers in the United States. An estimated 56,870 new cases are diagnosed annually, and 2,010 people die of the disease. Thyroid cancer is typically more aggressive in men than women and becomes increasingly lethal in those older than age 40. The dearth of data from well-designed trials has led to confusion over the optimal management strategies for individual patients. In this interview, Jochen Lorch, MD, MS, Assistant Professor of Medicine at Harvard...
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