Beating Cancer Cells at Their Own Game

For many patients with cancer, treatment resistance develops, leaving cancerous cells to continue to proliferate. Viewing the capability of cancer cells to develop resistance to drugs as a type of evolutionary game, researchers at the Cleveland Clinic developed a game assay using a model of anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) cells to measure and explain the interactions between drug-sensitive and drug-resistant cancer cells.  "Rather than searching ...
Continue reading

DNA Damage Repair Inhibitors Fight Small Cell Lung Cancer

Patients with small cell lung cancer (SCLC) often do not respond to immune checkpoint blockade therapy alone. However, researchers at the University of Texas MD Anderson Cancer Center now report that a combination of immune checkpoint blockade therapy and targeted therapies blocking DNA damage repair significantly shrinks tumors in mouse models of SCLC. "While the use of immunotherapy has revolutionized the way we treat lung cancer, we find that small cell lung cancers can escape the immune syst...
Continue reading

Like Smoking, Vaping Creates Cancer-Causing Changes

The last few years have seen a nearly 10-fold increase in electronic cigarette (e-cig) use, or "vaping," particularly among adult smokers and among adolescents who have never smoked a cigarette. E-cigs are frequently touted as a safer alternative to traditional cigarettes, but new research done at the University of Southern California (USC) reveals that vaping produces some of the same cancer-causing molecular changes to oral tissue that are produced by cigarette smoking. "The existing data show...
Continue reading

Is Heated Rather Than Burned Tobacco Safer to Inhale?

Electronic nicotine/non-nicotine cigarettes (e-cigarettes) and heat-not-burn (HNB) tobacco products such as those marketed as IQOS™ are branded as safer alternatives to traditional cigarette smoking. Cigarette companies claim that the amount of chemicals emitted from e-cigarettes and IQOS™ are significantly reduced compared to traditional cigarette smoke; however, no research is available to validate these claims. When researchers at Woolcock Institute conducted a study to determine the effect t...
Continue reading

How to Help Cancer Patients Quit Smoking

​ After a cancer diagnosis, nearly half of patients who smoke continue to do so, even though continued smoking can negatively impact the outcome of their disease. A team of researchers from Northwestern University's Feinberg School of Medicine and the University of Pennsylvania's Abramson Cancer Center has found that lengthening patients' use of an anti-smoking medication can lead to better smoking cessation outcomes for those who adhere to the treatment. "With the stress cancer patients are und...
Continue reading

© Copyright 2019 i3 Health. All rights reserved.