Noninvasive Nanoscale Test Accurately Detects Bladder Cancer

Researchers have developed an accurate, noninvasive diagnostic test that can be used for a number of cancers. Their success in applying this test to the detection of bladder cancer makes it the first to effectively utilize atomic force microscopy (AFM) for diagnostic purposes. Bladder cancer is one of the most common cancers and one of the most common causes of cancer-related death. If it is detected in stage 0, bladder cancer has a five-year survival rate of 98%; if it is detected at an advance...
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Nanoscale Liquid Biopsy Technique Reveals More About Cancer

​ Something intriguing occurs when nanoparticles come into contact with biological fluids: proteins attach themselves to the nanoparticle surfaces, forming what is called a "protein corona." This phenomenon has now resulted in a technique that could allow doctors and researchers to glean additional information from the blood of cancer patients. When researchers from the University of Manchester extracted injected liposomes—lipid-based nanoparticles used for drug delivery with minimal side effect...
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Nanodevice Delivers Immunotherapy Without Side Effects

​ Researchers at Houston Methodist have invented a nanodevice that delivers immunotherapy medications directly to a tumor in a single, sustained-release dose, dramatically reducing treatment-related side effects. Conventional immunotherapy, which involves systemic treatment administration, often results in significant side effects while failing to produce a sufficient antitumor immune response. Delivering immunotherapy medications intratumorally—directly within the tumor—has the potential to sol...
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Nanoparticles Enhance Chemotherapy Response

By combining tumor-modulating nanoparticles with chemotherapy regimens such as doxorubicin, scientists at the University of Toronto's Leslie Dan Faculty of Pharmacy have found a method to enhance chemotherapeutic efficacy and boost antitumor immunity. The researchers introduced hybrid polymer-lipid encapsulated manganese dioxide nanoparticles (PLMD NP) in breast cancer mouse models. These nanoparticles function by accumulating in the tumor and remodeling the tumor environment by generating oxyge...
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