Inflammatory Bowel Disease: Risk Factor for Prostate Cancer

In a recent study , inflammatory bowel disease (IBD) was found to be a potential precursor to prostate cancer. A twenty-year analysis of 1,033 men with IBD and 9,306 healthy men showed that those with IBD had a higher incidence rate of developing prostate cancer than those without IBD. IBD, which includes Crohn's disease and ulcerative colitis, is a common ailment in the US, afflicting approximately 1.6 million people, 1 million of them being men. The study, published in European Urology , found...
Continue reading

Genetic Factor Discovered in Metastatic Prostate Cancer

Because prostate cancer cases are often localized and controlled, men can survive many years after diagnosis. However, that is not the case for metastatic castration-resistant prostate cancer (mCRPC): after diagnosis, less than a third of men survive five years. In the treatment of prostate cancer, hormone therapy is commonly used to suppress androgen receptors in order to prevent testosterone from being produced, thereby killing the malignant tumor. Unfortunately, this does not work for mCRPC. ...
Continue reading

New Method Identifies Life-Threatening Prostate Cancer

Researchers at the University of York in York, England, have found a way to determine whether a patient's prostate cancer has spread beyond the prostate. This knowledge could be used to treat only those patients for whom therapeutic measures are necessary. "Unnecessary prostate treatment [not only has] physical consequences for patients and their families but is also a substantial financial burden on the NHS [National Health System], where each operation will cost around £10,000," commented the ...
Continue reading

In Black Men, Midlife PSA Screening Predicts Aggressive Prostate Cancer

​ The first study of its kind to focus exclusively on black men has found that a baseline measurement of prostate-specific antigen (PSA) performed at midlife predicts the later development of aggressive prostate cancer. "Black men in the US are 2.5 times more likely to die of prostate cancer compared to white men, yet screening studies to date have largely been focused on white men," stated co-senior author Lorelei Mucci, MPH, ScD, Associate Professor of Epidemiology at the Harvard T.H. Chan Sch...
Continue reading

Common Cause Links Small Cell Prostate and Lung Carcinomas

​ Researchers have discovered that the same set of oncogenes reprograms healthy human prostate and lung epithelial cells into small cell prostate cancer (SCPC) and small cell lung cancer (SCLC). This breakthrough, the first to clearly describe the steps in these cancers' shared evolution, could lead to the development of drugs targeting multiple types of small cell neuroendocrine carcinoma (SCNC) through a single mechanism. An unfortunate consequence has resulted from powerful targeted therapies...
Continue reading
© Copyright 2018 i3 Health. All rights reserved.