Herpes Zoster (Shingles) Vaccination After Autologous HSCT

​A phase 3 clinical trial reports that two doses of the adjuvanted recombinant zoster vaccine reduce the incidence of herpes zoster, commonly known as shingles, following autologous hematopoietic stem cell transplantation (HSCT).Patients receiving high-dose chemotherapy for certain types of malignancies, including multiple myeloma, non-Hodgkin lymphoma, Hodgkin lymphoma, acute myeloid leukemia, neuroblastoma, and germ cell tumors, are often administered autologous HSCT in order to replenish thei...
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Prostate Cancer: Carbon Ion Radiotherapy Reduces Future Risk

​A new study reports that compared with photon radiotherapy, carbon ion radiotherapy reduces the risk of subsequent primary tumors in patients with localized prostate cancer."The risk of subsequent primary cancers in patients with prostate cancer after treatment with photon radiotherapy is small in absolute numbers, but it is higher than that after surgical treatment," explain the authors of the study, which was published in The Lancet Oncology. "Carbon ion radiotherapy has a theoretically lower...
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Preventing Venous Thromboembolism in Patients With Cancer: An Interview With Philip Wells, MD, FRCPC, MSc

​Venous thromboembolism is the third most common vascular condition after heart attack and stroke, affecting between 300,000 and 600,000 individuals in the United States each year. Patients with active cancer are at increased risk, with a 9.6% chance of developing symptomatic thrombosis during the first six months of chemotherapy. In this interview with i3 Health, hematologist Philip Wells, MD, FRCPC, MSc, Chair and Chief of the Department of Medicine at the University of Ottawa and The Ottawa H...
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Apixaban Prevents Venous Thromboembolism in Patients With Cancer

​A team of Canadian researchers has found that apixaban reduces the occurrence of venous thromboembolism in cancer patients who are starting chemotherapy and are at intermediate to high risk for this condition.A blood clot that forms in the veins, venous thromboembolism is the third most common vascular condition after heart attack and stroke, affecting between 300,000 and 600,000 individuals in the United States each year. Patients with active cancer are at increased risk, with a 9.6% chance of...
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Chemotherapy Agents Differ in Long-Term Cardiac Risks

​Although anthracyclines—chemotherapeutic agents that are extracted from Streptomyces bacterium—can be highly effective in the fight against various pediatric cancers, they carry a long-term risk of cardiovascular disease that continues to impact patients well into their adult lives. While this much is well known, the impact of specific anthracyclines on cardiac risk has not been adequately studied. In a study published in JAMA Oncology, researchers have now identified the relative long-ter...
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